2009:

Kreutz S, Koch M, Böttger C, Ghadban C, Korf HW, Dehghani F: 2-Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal cannabidiol-sensitive receptors on microglial cells. Glia 2009 Feb; 57:286-294.
Abstract at PubMed


2008:

Niederberger E, Kühlein H, Geisslinger G: Update on the pathobiology of neuropathic pain. Expert Rev Proteomics 2008 Dec; 5:799-818.
Abstract at PubMed

Pierre S, Maeurer C, Coste O, Becker W, Schmidtko A, Holland S, Wittpoth C, Geisslinger G, Scholich K: Toponomics Analysis of Functional Interactions of the Ubiquitin Ligase PAM (Protein Associated with Myc) during Spinal Nociceptive Processing. Mol Cell Proteomics 2008 Dec; 7:2475-2485.
Abstract at PubMed

Proschak E, Sander K, Zettl H, Tanrikulu Y, Rau O, Schneider P, Schubert-Zsilavecz M, Stark H, Schneider G: From molecular shape to potent bioactive agents II: Fragment-based de novo design. ChemMedChem 2008 Dec 4; [Epub ahead of print]
Abstract at PubMed

Proschak E, Zettl H, Tanrikulu Y, Rau O, Weisel M, Kriegl JM, Rau O, Schubert-Zsilavecz M, Schneider G: From molecular shape to potent bioactive agents I: Bioisosteric replacement of molecular fragments. ChemMedChem 2008 Dec 4; [Epub ahead of print]
Abstract at PubMed

Coste O, Brenneis C, Linke B, Pierre S, Maeurer C, Becker W, Schmidt H, Gao W, Geisslinger G, Scholich K: Sphingosine 1-phosphate modulates spinal nociceptive processing. J Biol Chem 2008 Nov 21; 283:32442-32451.
Abstract at PubMed

Köberle A, Zettl H, Greiner C, Wurglics M, Schubert-Zsilavecz M, Werz O: Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase and 5-lipoxygenase. J Med Chem 2008 Nov 19; [Epub ahead of print]
Abstract at PubMed

Schneider G, Hartenfeller M, Reutlinger M, Tanrikulu Y, Proschak E, Schneider P: Voyages to the (un)known: Adaptive design of bioactive compounds. Trends Biotechnol 2008 Nov 10; [Epub ahead of print]
Abstract at PubMed

Maier TJ, Tausch L, Hoernig M, Coste O, Schmidt R, Angioni C, Metzner J, Groesch S, Pergola C, Steinhilber D, Werz O, Geisslinger G: Celecoxib inhibits 5-lipoxygenase. Biochem Pharmacol 2008 Oct ; 76:862-872.
Abstract at PubMed

Niederberger E, Geisslinger G: The IKK-NF-kappaB pathway: a source for novel molecular drug targets in pain therapy? FASEB J 2008 Oct; 22:3432-3442.
Abstract at PubMed

Popp L, Häussler A, Olliges A, Nüsing R, Narumiya S, Geisslinger G, Tegeder I: Comparison of nociceptive behavior in prostaglandin E, F, D, prostacyclin and thromboxane receptor knockout mice. Eur J Pain 2008 Oct: Epub ahead of print.
Abstract at PubMed

Schiffmann S, Sandner J, Schmidt R, Birod K, Wobst I, Schmidt H, Angioni C, Geisslinger G, Grösch S: The selective COX-2-inhibitor celecoxib modulates sphingolipid synthesis. J Lipid Res 2008 Aug 18; [Epub ahead of print]
Abstract at PubMed

Schmidtko A, Gao W, König P, Heine S, Motterlini R, Ruth P, Schlossmann J, Koesling D, Niederberger E, Tegeder I, Friebe A, Geisslinger G: cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I. J Neurosci 2008 Aug; 28:8568-8576.
Abstract at PubMed

Schiffmann S, Maier TJ, Wobst I, Janssen A, Corban-Wilhelm H, Angioni C, Geisslinger G, Grösch S: The anti-proliferative potency of celecoxib is not a class effect of coxibs. Biochem Pharmacol 2008 Jul; 76:179-187.
Abstract at PubMed

Wobst I, Schiffmann S, Birod K, Maier TJ, Schmidt R, Angioni C, Geisslinger G, Grösch S: Dimethylcelecoxib inhibits prostaglandin E2 production. Biochem Pharmacol 2008 Jul; 76:62-69.
Abstract at PubMed

Coste O, Pierre S, Marian C, Brenneis C, Angioni C, Schmidt H, Popp L, Geisslinger G, Scholich K: Antinociceptive activity of the S1P-receptor agonist FTY720. J Cell Mol Med 2008 Jun; 12:995-1004.
Abstract at PubMed

Webler AC, Popp R, Korff T, Michaelis UR, Urbich C, Busse R, Fleming I: Cytochrome P450 2C9-induced angiogenesis is dependent on EphB4. Arterioscler Thromb Vasc Biol 2008 Jun; 28:1123-1129.
Abstract at PubMed

Huwiler A, Pfeilschifter J: New players on the center stage: sphingosine 1-phosphate and its receptors as drug targets. Biochem Pharmacol 2008 May; 75:1893-1900.
Abstract at PubMed

Michel AA, Steinhilber D, Werz O: Development of a method for expression and purification of the regulatory C2-like domain of human 5-lipoxygenase. Protein Expr Purif 2008 May; 59:110-116.
Abstract at PubMed

Brenneis C, Coste O, Schmidt R, Angioni C, Popp L, Nusing RM, Becker W, Scholich K, Geisslinger G: Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice. J Cell Mol Med 2008 Apr; 12:639-648.
Abstract at PubMed

Michaelis UR, Xia N, Barbosa-Sicard E, Falck JR, Fleming I: Role of cytochrome P450 2C epoxygenases in hypoxia-induced cell migration and angiogenesis in retinal endothelial cells. Invest Ophthalmol Vis Sci 2008 Mar; 49:1242-1247.
Abstract at PubMed

Rau O, Zettl H, Popescu L, Steinhilber D, Schubert-Zsilavecz M: The treatment of Dyslipidemia-what's left in the pipeline? ChemMedChem 2008 Feb; 3:206-221.
Abstract at PubMed

Fleming I: Vascular cytochrome p450 enzymes: physiology and pathophysiology. Trends Cardiovasc Med 2008 Jan; 18:20-25.
Abstract at PubMed

Johann AM, Weigert A, Eberhardt W, Kuhn AM, Barra V, von Knethen A, Pfeilschifter JM, Brüne B: Apoptotic cell-derived sphingosine-1-phosphate promotes HuR-dependent cyclooxygenase-2 mRNA stabilization and protein expression. J Immunol 2008 Jan; 180:1239-1248.
Abstract at PubMed

Namgaladze D, Kollas A, Brüne B: Oxidized LDL attenuates apoptosis in monocytic cells by activating ERK signaling. J Lipid Res 2008 Jan; 49:58-65.
Abstract at PubMed